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Ketamine Clinics in South Dakota

1 verified ketamine clinics across 1 city in SD.

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All Clinics in South Dakota

Ketamine Therapy in South Dakota: FAQ

How many ketamine clinics are there in South Dakota?

There is 1 ketamine clinic in South Dakota in our directory, across 1 city.

Which cities in South Dakota have ketamine clinics?

Ketamine clinics in South Dakota are located in Rapid City.

Is ketamine therapy legal in South Dakota?

Yes. Ketamine therapy is legal in all 50 states, including South Dakota, when prescribed and administered by licensed clinicians. Generic ketamine is prescribed off-label for depression and pain, while Spravato (esketamine) is FDA-approved for treatment-resistant depression and is administered at certified clinics.

How much does ketamine therapy cost in South Dakota?

Most U.S. clinics charge roughly $400–$800 per IV infusion, with a typical induction course of about six sessions. Intramuscular (IM) injections often cost less, and Spravato is frequently covered by insurance for eligible diagnoses. Contact clinics directly for exact pricing — many quote a full-course price by phone.

What is the highest-rated ketamine clinic in South Dakota?

Based on public Google reviews, Manlove Brain+Body Health in Rapid City is currently the highest-rated ketamine clinic in South Dakota, with a 4.8 rating across 692 reviews. Ratings change over time, so check our up-to-date ranking of the best clinics in South Dakota.

New to ketamine therapy? Start with our guides on costs, Spravato vs. generic ketamine, and what to expect at a first session.